“So she left this meeting where she was trying to hold the Muslim Brotherhood to account for something and we’re here just doing a dumb movie score,” Clooney said with a laugh.

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“I was like, ‘Yeah, this is really important stuff we’re working on here.’”

RELATED: Watch George Clooney Describe the Moment He Met Amal in the Most Loving Way

The new parents recently celebrated Amal’s 40th birthday with a quick trip to Big Sur. The two were seen flying out of L.A. on Saturday, the day of her birthday, and returning around the same time the next day.

It marked Amal’s first birthday since welcoming twins Ella and Alexander last June. The 8-month-old twins arrived just a few months shy of the couple’s third wedding anniversary in September.

Next Guest Needs No Introduction with David Letterman with George Clooney streams Friday, Feb 9 on Netflix.